Abstract

PHYTOCHEMICAL INVESTIGATION & ANTHELMINTIC ACTIVITY OF DIFFERENT EXTRACTS OF ROOTS OF TECTONA GRANDIS

Rizwan Ul Hasan, Shahid Jamil and Shadab Alam*

ABSTRACT

The plant Tectona grandis Linn. (TG) commonly known as 'Teak' (English) is a deciduous tree belongs to the Family “Verbenaceae”. The phytochemical investigation of different extracts and Anthelmintic activity of the methanolic and aqueous extracts (roots) of Tectona grandis were performed. Phytochemical screening showed the presence of alkaloids carbohydrates, phenolic compounds, flavonoids, sterols, glycosides and saponins. Methanolic and aqueous roots extracts of Tectona grandis were evaluated separately on developed Indian earthworm (Pheretima posthuma) and the activities were compared with standard drug piperazine citrate. It was found that methanol and aqueous extracts of Tectona grandis exhibited dose dependant action and inhibition of spontaneous motility (paralysis) and death of earthworms. The results showed that the methanolic extracts were more potent than aqueous extracts.

Keywords: Tectona grandis, Phytochemical investigation, Anthelmintic activity, Pheretima posthuma.