Abstract

ANALYSIS AND IDENTIFICATION OF ENSA AS A TARGET MOLECULE FOR DIABETES MELLITUS USING BIOINFORMATICS TOOLS

Sudha D.*, Shoba K. and Asha S.

ABSTRACT

Diabetes mellitus, which is simply referred to as diabetes these days, is a metabolic disorder which in particular affects the metabolism of carbohydrates. The condition requires medical treatment and, more often than not, a number of lifestyle changes. The target gene for Diabetes mellitus is identified through NCBI data base. Using BLASTP the similarities of the target gene was identified. The primary analysis were done through coils, protparam and secondary analysis were done through YASPIN. SMART. The target gene had been modeled in Mdeller9v6 server and visualized in Rasmol. The results obtained from the investigation would have a scope for drug designing in the future studies. The current work focus on functional characterization of target gene which is responsible for Diabetes mellitus.

Keywords: Diabetes mellitus, Ncbi, BLASTP, YASPIN.SMART, Mdeller9v6, ENSA.