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RAGE- AN OVERVIEW
Vimalavathini R.*, Srinithi S., Vishvaja S., Thamizharasi S. and Yuvaraj G.
ABSTRACT Receptor for advanced glycated end products (RAGE) are trans-membrane receptor which has been implicated in physiological and pathological pathways of various diseases like cardiovascular diseases, cancer, neurodegenerative and autoimmune diseases. Though a target for various ligands its interaction with advanced glycated end products (AGE) has been implicated in the development and deterioration of various diseases and hence has become a potential therapeutic target for alleviation of these diseases. This literature review summarizes the pathological role of the RAGE in these diseases. Keywords: AGE, RAGE, diseases. [Download Article] [Download Certifiate] |