Abstract

A REVIEW ON RECENT APPROACHES IN TASTE MASKING TECHNOLOGIES AND THEIR REGULATORY CONSIDERATIONS

Sagar C. Kamble*, Mansi C. Kanchanwar, Pravin Suruse, Jagdish Baheti, Jayshree B. Taksande, Millind J. Umekar

ABSTRACT

Tablet is a solid dosage form of active drug or active drug with excipients, prepare by moulding or by compression. There are many active drugs which has bitter or unpleasant taste for geriatrics and paediatrics patient, by which they avoid to get consumed that drug, hence taste masking of the drug is important. Taste masking is a process which leads to reduction of a undesirable taste that would exist. Many techniques are developed which not orally improved the taste of product, but also the stability of formulation and performance of the product. The various factors which affect section of taste masking technology are- Extent of bitter taste of the API, Dose of active pharmaceuticals, drug particle shape and size distribution, dosage form, drug stability, ionic characteristics of the drug. To have the better taste masking of pharmaceutical drug we must have to consider the regulatory guidelines which give the conditions which shows safe food additive can be used in pharmaceutical production and proportion of foods beverages and pharmaceutical dosage form. These conditions are written in code of federal regulation, title 21, parts 173. Some regulatory aspects of ion exchange resins produced by ion exchange limited are Indion 204, 214, indion 234 and 234 S, indion 254, indion 264, indion 464, these review paper on recent approaches in taste masking technologies and their regulatory considerations TMT.

Keywords: Taste Masking Technologies, Physiology of Taste, Factors and Approaches in Taste Masking Technologies, Regulatory Considerations.