Abstract

ANTIMICROBIAL AGENTS AND ANTIBACTERIAL ANTIBIOTICS: AN OVERVIEW

Thorat Sheela Shivaji*, Mali Ramling Dnyaneshwar, Inamdar Nassruddin Rafik and Upadhye Shashikant Sudarshan

ABSTRACT

The bacteria were first identified by the scientist Van Leeuwenhoek. Bacteria are simple celled microorganism; it consists of the cell wall, cell membrane. Thus, the cell wall is made up of peptidoglycan. There are two types of bacteria, gram-positive and gram-negative bacteria. The antibiotics are the chemotherapeutic agents which are effective against the bacterial infection. Furthermore, The antimicrobial agents are the drugs which are responsible for killing and inhibiting the growth of microorganism. The antibacterial antibiotics constitute the Tetracycline, quinolone antibacterial, beta-lactam antibiotics has classed such as penicillin, cephalosporin. This comprehensive study of antibacterial antibiotics includes classification, History, nomenclature, chemical name, mechanism of action, structural activity relationship, Pharmacokinetics, uses, side effect, toxicities of penicillin, cephalosporin, tetracycline, quinolone antibacterial agents, glycopeptide antibiotics.

Keywords: Antibacterial antibiotics, Penicillin, Cephalosporin, Tetracycline, Quinolone, glycopeptide antibiotic.