Abstract

THE MOLECULAR NEUROBIOLOGY BEHIND BIPOLAR DISORDER: A REVIEW ARTICLE

Sohini Dutta*, Dr. Kavitha S. Raj 

ABSTRACT

Bipolar Disorder, a severe psychiatric disease, is associated with alterations in the Central Nervous System. Because of the broad spectrum over which these abnormalities arise, the exact causative effects are not yet known. Several studies in the past have tried to uncover the biological factors involved in the pathophysiology using various biochemical and neuroendocrine strategies. Recent studies have however implicated critical signal transduction pathways as an integral part of the pathophysiology and treatment of Bipolar Disorder. The neurobiology underlying the disease has been reviewed in this article.

Keywords: Bipolar Disorder, Neurobiology, Pathophysiology, Signal transduction pathway, Brain structure, Cerebro-Spinal Fluid (CSF).