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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

FORMULATION AND EVALUATION OF TIME DELAYED CAPSULE DEVICE FOR CHRONOTHERAPEUTIC DELIVERY OF SALBUTAMOL SULPHATE

Gogulapati Neeharika*, Balasubramanian Valli Manalan, Rama Rao Nadendla

ABSTRACT

Chronotherapeutic drug delivery system, drug availability is matched with rhythms of the disease according to the time structure which results in the less adverse effects and maximum therapeutic effects. Salbutamol sulphate is short acting, selective beta-2 adrenergic receptor against used in the treatment of asthma and COPD. The main aim of this study was to explore to the feasibility of time dependent capsule device for chronotherapeutic delivery of salbutamol sulphate to treat nocturnal symptoms of asthma. In the present research work, we have attempted to develop pulse in cap system by using hydrophilic erodible tablet plugs and time delayed capsule device of salbutamol sulphate by using HPMC, Xanthan gum and Guar gum polymers.

Keywords: Pulsatile drug delivery system; Pulse in cap system; Erodible tablet plugs and Time delayed capsule device.

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