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SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF DIACEREIN AND GLUCOSAMINE SULPHATE IN PHARMACEUTICAL FORMULATION
Shubhangi A. Choudhari*, Dr. Dinesh Chaple, Manish Mohture, Kanchan Ghode, Srushti Wairagade
ABSTRACT A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of Diacerein and Glucosamine Sulphate in bulk and pharmaceutical dosage forms. Diacerein shows maximum absorbance at 342 nm and Glucosamine Sulphate at 258 nm. Beer’s law was obeyed in the concentration range of Diacerein at 1-50 μg/ml and Glucosamine Sulphate at 1-60 μg/ml. The method was found to be precise, accurate and specific. The proposed method was successfully applied to estimation of Diacerein and Glucosamine Sulphate in combined dosage form. The method was validated according to ICH guidelines. Keywords: Simultaneous Spectrophotometric Analysis, Diacerein, Glucosamine sulphate. [Download Article] [Download Certifiate] |