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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

REVIEW OF ACYCLOVIR ANALYSIS IN PHARMACEUTICAL PREPARATIONS AND BIOLOGICAL MATRICES

Edtyva Monicha, Regina Andayani and Harrizul Rivai*

ABSTRACT

Acyclovir is an active antiviral drug for treating Herpes Simplex Virus (HSV) types 1 and 2. This drug is also useful in the treatment of infections due to varicella-zoster virus. Acyclovir preparations on the market are in the form of tablets, ointments, or intravenous injections. This review article discusses the acyclovir analysis method in pharmaceutical preparations and biological matrices. Several spectrophotometric, voltammetry, capillary electrophoresis analysis methods, and thin-layer chromatography are used to determine acyclovir in raw materials, and pharmaceutical preparations. Also, high-performance liquid chromatography (HPLC) and mass spectrophotometry (MS) methods can be used to analyze acyclovir in various biological matrices (eg plasma, urine).

Keywords: Acyclovir, spectrophotometry, voltammetry, electrophoresis, HPLC, MS.

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