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All | Since 2019 | |
Citation | 5450 | 3969 |
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INTERLEUKIN 17 AND ORAL SQUAMOUS CELL CARCINOMA – A SHORT REVIEW
*Dr. Pooja Bhagwat, Dr. Rucha Diwakar Gore, Dr. Prashant Rao and Dr. Venkatesh V. Kulkarni
ABSTRACT Interleukin-17A (IL-17A), a proinflammatory cytokine mainly produced by T helper 17 cells, exerts protumor or antitumor effects in different cancer entities. However, the exact role of IL-17A in carcinogenesis and progression of oral squamous cell carcinoma (OSCC) remains unclear. Besides, IL- 17A enhanced cell migration and invasion in OSCC cell line. With the intricate role IL-17 plays in cancer pathophysiology, substantiation is now growing which ropes the ability of IL-17 to act as a key diagnostic marker, distinguishing between benign and malignant pathology as well as predicting prognosis for Oral Squamous Cell Carcinoma. Keywords: Interleukin -17, Oral Cancer, Oral Squamous cell carcinoma. [Download Article] [Download Certifiate] |