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DEVELOPMENT AND VALIDATION OF UV-VISIBLE SPECTROPHOTOMETRICAL METHOD FOR THE ESTIMATION OF ASPIRIN-DEXLANSOPRAZOLE COMBINATION
*Amala Sara George, Kunnath Kamarunissa, Athira J. S., Dr. Prasanth S. S.
ABSTRACT
Rapid, simple and specific analytical methods using UV spectrophotometry was established for the estimation of drugs that are used as proton pump inhibitors. The developed methods were validated according to ICH guidelines for linearity, precision, accuracy, limit of detection, limit of quantification and robustness. The proton pump inhibitors are used as an effective cure for acid-peptic disorders by blocking the proton pumps (H+_K+ ATPase) on the walls of the esophagus, stomach and duodenum. The significance of these proposed Keywords: Vierodt’s method, Dexlansoprazole, Aspirin, absorption maxima, percentage recovery. [Download Article] [Download Certifiate] |