SIMULTANEOUS ESTIMATION OF ACECLOFENAC AND PARACETAMOL ORODISPERSIBLE TABLETS BY SPECTROPHOTOMETRIC METHOD
*Manasa Gururaj1, Snehalatha1, Yogananda R1, H.S Basavaraja2, Santhose Varma1, Bharathi D.R3
1PG Dept. of Pharmaceutics, S.J.M College of Pharmacy, Chitradurga, Karnataka, India.
2PG Dept. of Pharmachemistry, S.J.M College of Pharmacy, Chitradurga, Karnataka, India.
3PG Dept. of Pharmacology, S.J.M College of Pharmacy, Chitradurga, Karnataka, India.
ABSTRACT
Here an attempt has been made to develop a simple, economic,
sensitive and reproducible spectrophotometric method for quantitative
estimation of Aceclofenac (ACE) and Paracetamol (PARA) from bulk
drug and in pharmaceutical formulations. In this spectroscopic
method, simultaneous estimation of ACE and PARA at max 274nm
and 243.5nm respectively by utilizing spectrum mode of analysis in
U.V visible spectrometer. The method employing simultaneous
equation is very simple method and can be employed for routine
analysis of Aceclofenac and Paracetamol. The proposed method is
highly sensitive and successfully applied for the analysis of
Aceclofenac and Paracetamol in tablet formulation.
Keywords: Aceclofenac (ACE), Paracetamol (PARA).
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