Abstract

METABOLOMICS: THE STUDY OF METABOLITES

Nutan Rao*, Akshata Desai, Shraddha Gaur and Madhusudan Bhoir

ABSTRACT

Metabolomics is the newest ―omics‖ approach for analysis of metabolites. Metabolomics measure the metabolites which are present in the biological samples to obtain ‗metabolomes‘. One of the most popular aims of metabolomic study is biomarker discovery. This biomarker helps us in identifying the disease state. Various analytical techniques are used for metabolite measurements. Most commonly used technique is mass spectrometry due to its high specificity and excellent limit of detection. Metabolomics has several applications. Typical data handling practices, data outputs and instrumentation for these experiments are introduced in this article. Description of pharmacogenomics and pharmacoproteomics is also provided. A case study involving the use of metabolomics approach is also described in this article.

Keywords: Metabolomics, Metabolite, Metabolomes, Omics System.