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UTILIZATION OF CLOVE OIL TO REDUCE SOME BIOCHEMICAL DISTURBANCES INDUCED BY HIGH FAT DIET IN RATS
Naglaa E. Mohamed* and Mervat M. Anwar
ABSTRACT
Twenty four male albino rats were divided into four groups. Group 1 (control) fed on a standard diet, group 2 was administered orally clove oil (200 mg/kg b.wt/day), group 3 fed on high fat diet (HFD) by adding saturated palm oil to the standard diet (15 g oil /100 g diet) and group 4 was administered orally clove oil + high fat diet for 60 days. Thiobarbituric acid reactive substance (TBARS), glutathione (GSH) content and catalase activities (CAT) were estimated in cardiac and hepatic tissues. Serum lipase, total lipids, phospholipids, cholesterol, triglycerides, lactate dehydrogenase (LDH), creatinine kinase (CK), Insulin, homeostasis insulin resistance and plasma glucose were determined. Also, serum free thyroxin (FT4) and free triiodothyronine (FT3) were estimated. Serum tumor necrosis factor-α (TNF-α) and 8- Keywords: High-fat diet, Clove oil, Lipid profile, DNA oxidative stress, Tumor necrosis factor-?, Thyroid hormones, Insulin. [Download Article] [Download Certifiate] |