Abstract

EVALUATION OF ANTI-MICROBIAL (IN-VITRO) ACTIVITY OF AMARANTHA CURQMINT TABLET

*Dr. Sanjay Nipanikar, Dr. Snehal Agnihotri, Dr. Suneeta Panicker, Nivedita Shelke

ABSTRACT

In modern medicine, adverse effects, resistance and expensiveness associated with the use of antibiotics are of a great concern. There is an urge for development of prevention and treatment options that are natural, safe, effective and economical. Ari Healthcare Pvt. Ltd. has conceptualized and developed a formulation called “Amarantha CurQmint Tablet” for treatment of halitosis, cough, common cold and sore throat. In the present study, Amarantha CurQmint Tablet was tested for anti-microbial activity against oral cavity pathogens such as E. coli, Staph. auerus and Candida albicans in comparison with marketed product, methanol and standard drug i.e. Chlorhexidine. Various concentrations of Amarantha CurQmint Tablet i.e. 2%, 3% and 4% showed more zone of inhibition (of 25 mm each) against Staph. auerus than Methanol (11 mm) and Chlorhexidine (19 mm). Also, 3% and 4% concentrations of Amarantha CurQmint Tablet showed more zone of inhibition (of 23 mm and 25 mm respectively) against E. coli than Methanol (11 mm) and Chlorhexidine (19 mm). All concentrations of Amarantha CurQmint Tablet i.e. concentration of 1%, 2%, 3% and 4% showed more zone of inhibition (of 20 mm, 25 mm, 25 mm, and 25 mm, respectively) against Candida albicans than Methanol (11 mm) and standard drug Chlorhexidine (19 mm). The zones of inhibitions of Marketed Product group against all three strains were 0, which was suggestive that Marketed Product has no antimicrobial activity against all three microorganisms. The study concluded that Amarantha CurQmint Tablet possesses antibacterial and antifungal activities and can be used in halitosis, cough, common cold and sore throat.

Keywords: CurQmint Tablet, Anti-microbial, E. coli, Staph. auerus, Candida albicans.