A REVIEW ON- TREATMENT OF PARKINSONS DISEASE
*Ravi Dubey, Saba shaikh, Dr.Y.M Joshi and Dr. Vilasrao J. Kadam
Department of Pharmacology, Bharati Vidyapeeth’s College of Pharmacy, Sector 8, C.B.D., Belapur, Navi Mumbai 400614, Maharashtra, India.
ABSTRACT
Parkinsons disease (PD) is a movement disorder that is characterized
by selective damage to dopaminergic nigrostriatal neurons that lead to
motor deficits including rigidity, tremor, bradykinesia and possibly
dementia.The primary pathology of PD is believed to involve the loss
of dopaminergic neurons in substantia nigra, with a resultant decline
of dopamine in the striatum.These symptoms are treated with a range
of drugs that include drugs acting on brain cholinergic system and
drugs acting on brain dopaminergic system.This review also describe
some complementary therapies.
Keywords: Parkinsons disease, Levodopa, COMT inhibitors, carbidopa, MAO inhibitors.
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