Abstract

STANDARDIZATION OF TRIKATU TABLET AN AYURVEDIC POLYHERBAL FORMULATION

Dr. Abdeli Bhadarva*, Vd. Hitesh Vyas, Dr. Jasmin Gohel, Dr. Yogesh Manani and Dr. Hansraj Barjod

ABSTRACT

According to the Ayurvedic principles, a drug should not be only efficacious, but also easily available and a drug or therapy should not be only having pacifying effect on disease, but also it must not create any adverse effect or complication.[1] Efficacy of formulation depends on their genuineness of herbs used. Authentication of herbs by anatomical studies is first and fundamental step for standardization of herbal formulation. In this study Pharmacognostic investigations like macroscopic, microscopic and chemical studies like preliminary phytochemical and physic - chemical constants of Trikatu Churna were studied. The observations were systematically recorded. Pharmacognostical findings of raw drugs (Olioresins, Starch grains, Parenchyma, Vessels, Trichomes, Fibre, Spiral vessels, Pitted vessels, Starch crystals, Prysmatic crystals, Stone cells, Fibre, Oil globules, Epidermal cells etc.) confirm the authentication of ingredients present in the finished product. Organoleptic features of Trikatu teblet made out of the crude drugs were within the standard range as mentioned in the classic. The pH value of Trikatu teblet was 5.5, Loss on drying was 11.9%w/w, Ash Value was 7.35% w/w, Acid insoluble ash value was 0.94% w/w, Water-soluble extract was 6.56 % w/w, Methanol soluble extraction was 10.36 % w/w. Uniformity of tablet was found at 614 mg highest weight and 509 mg Lowest weight; 545 mg Average weight.

Keywords: Agnimandya, Anorexia, Pharmacognosy, Pharmaceutics, Standardization, Trikatu tablet.