Abstract

TRANSUNGUAL DRUG DELIVERY SYSTEM: A REVIEW

Bhandari Neeraj*, Sharma Aman, Kohal Rupali, Rana Shabnam, Thakur Jagrity and Dr. Gupta Rajesh

ABSTRACT

In recent past, medicated lacquers specially designed for the nail diseases, strike the formulation field. Nail diseases like onycomycosis, nail psoriasis, yellow nail syndrome, paronychia and many more, being cured successfully using medicated lacquers. This avoids the oral toxicity of anti fungal drugs and provides longer contact time at the site of actio. The purpose of this review is to explore the difficulties in penetration of drug across nail plate & enhancement of bioavailability of antifungal drug. The existing clinical evidence suggests that a key to successful treatment of fungal diseases by topical antifungal product lies in ineffectively overcoming the nail barrier. Recent focus is emphasizing on development of a promising antifungal treatment in form of nail lacquer owing to its beneficial advantages.

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