Abstract

DENGUE FEVER: A GLOBAL HUMAN THREAT: A RESEARCH OF LITERATURE BY HERBAL TREATMENT

*Harshrahsinh Rana, Aakash Vaghela, Dr. Pragnesh Patani

ABSTRACT

As the outbreaks of Dengue fever increasing in India, one state after other getting affected, it is very essential to know more about this disease and prevalence, any change in the viral strain, severity of the disease pattern, early detection of the virus and early management of the disease resulting in good recovery. Population growth, rapid urbanization, increase in international travel from endemic areas and global warming are playing a major role in disease spread. Measures should be taken to control the aforementioned causes to prevent disease spread and reduce epidemic flare up. Dengue is an acute viral illness caused by RNA virus of the family Flaviviridae and spread by Aedes mosquitoes. Presenting features may range from asymptomatic fever to dreaded complications such as haemorrhagic fever and shock. A cute-onset high fever, muscle and joint pain, myalgia, cutaneous rash, haemorrhagic episodes, and circulatory shock are the commonly seen symptoms. Oral manifestations are rare in dengue infection; however, some cases may have oral features as the only presenting manifestation. Early and accurate diagnosis is critical to reduce mortality. Although dengue virus infections are usually self-limiting, dengue infection has come up as a public health challenge in the tropical and subtropical nations. This article provides a detailed overview on dengue virus infections, varied clinical manifestations, diagnosis, differential diagnosis, and prevention and treatment.

Keywords: Dengue, Flaviviridae, polymorphism, MAC-ELISA, NS1 Protein, Break bone fever, cutaneous rash, dengue virus, dental and public health, haemorrhagic diathesis, oral manifestations.