Abstract

INVITRO ANTIOXIDANT AND ANTICOAGULANT ACTIVITY OF RED MARINE ALGAE SPECIES GRACILARIA FOLIFERA

P. Pandian* and K. Kathiresan

ABSTRACT

Disorders in blood coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). we aimed to evaluate the possible invitro antioxidant and anticoagulant effect of marine algae extracts of Gracilaria folifera. The algae were collected from different locations of Mandapam area, Tamilnadu. The algae extracted with ethanol solvent the antioxidant assay DPPH photometric, Superoxide radical scavenging activity and anticoagulant assay the APTT, PT, TT assay were performed with standard kit. the concentration for antioxidant is 125,250,500,1000 mcg/ml and for anticoagulant from 2mg/ml to 20mg/ml the result was tabulated and the1000 mcg/ml possess maximum antioxidant activity ethanol and the anticoagulant as APTT value for 20mg/ml is 158sec, PT values is 36sec and TT values is 68sec respectively.

Keywords: Gracilaria folifera, antioxidant, anticoagulant, ethanol.