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ANTI - GLAUCOMATOUS ACTIVITY OF ETHANOLIC EXTRACT OF ERYTHRINA VARIEGATE Lam. LEAVES
R. Krishnaveni*, Dr. S. Karpagam Kumara Sundari and Mr. K.A.S. Mohammed Shafeeq
ABSTRACT Objective: The aim of this study is to evaluate the anti – glaucomatous activity of Ethanolic extract of Erythrina variegate Lam. Leaves by using carbomer induced glaucoma in rabbits. Methods: Extraction was done by Continuous Hot Percolation method, analyzed by FTIR and HPTLC method and estimated anti - cholinesterase activity (in vitro) and evaluated anti- glaucomatous activity using Rabbit model. Result: 2% ethanolic extract of Erythrina variegate (EEEV) eye drops possess anti – glaucomatous activity. Conclusion: The study affirmed that the ethanolic extract of Erythrina variegate (2%) eye drops produced desirable changes in Intra ocular Pressure (IOP). Keywords: Anti- glaucomatous activity, Erythrina variegate, EEEV, Carbomer, IOP. [Download Article] [Download Certifiate] |