Abstract

ASSESSMENT OF ANTIMICROBIAL AND ANTIHELMINTIC ACTIVITY OF KRIMIGHATINI VATIKA

*Dr. Vilas Chadchan M.D.(Ayu), Dr. Pramod C. Baragi M.D.(Ayu) Ph.D., Dr. Kashinath Hadimur M.D. (Ayu) Ph.D. and Dr. K. A. Patil M.D.(Ayu)

ABSTRACT

Disease and death have always attracted the attention of human mind. Pathogenic micro organisms are the root cause of majority of diseases in human beings. Many naturally occurring and synthetic chemicals are discovered and developed as antibiotics to control or kill the micro organisms. Micro & macro organisms in Ayurveda are called as Krimi which include bacteria, fungi, parasites etc. There are many Krimighna dravyas used to treat Krimi. The present study is carried out on Antimicrobial and antihelmintic activity of Krimighatini Vatika to provide scientific evidence for Krimighna property in particular. Krimighatini Vatika was prepared as per Bhaishajya Ratnavali. Subjected to antimicrobial activity with Cup plate method, Disc diffusion method. By using different concentrations of test solutions against Eschericia coli, Staphylococcus Aures, Bacillus Subtilis, Klebsiella Pneumonae, Candida albicans, Aspergillu’s niger. Chroramphenical and Flucanazole were used as standard antibacterial & antifungal drugs respectively. Antihelmintic activity was conducted on earth worms & round worms by method of Ajaiyeoba et.Al. with minor modifications. Krimighatini Vatika with different concentrations have shown sensitivity against Klebsiella Pneumonae only in Disc diffusion method. Surprising results were noted in antihelmintic activity against Earth worms & round worms.

Keywords: Disc diffusion, Cup plate, Antimicrobial, Krimighatini Vatika, Chloromphenicol, Flucanazole. Antihelmintic.