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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

FORMULATION AND EVALUATION OF GABAPENTIN MATRIX TABLET USING DIFFERENT GRADES OF SODIUM ALGINATE

Y. B. Raut* and A. S. Dubey

ABSTRACT

The objective of work was to prepare and characterize gabapentin matrix tablet using sodium alginate LF5/60, LF10/60 and LF240 by direct compression method. From all the formulations, optimized formulation was combined with Cellulose acetate phthalate & Cellulose acetate butyrate for effect on release. Total 15 formulations were prepared and optimized formulation were evaluated by X-ray diffractometry (XRD), Differential scanning Calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) and Scanning electron microscopy (SEM). The results obtained showed that the formulations of Gabapentin prepared with combination sodium alginates and CAP has controlled release over 24 hrs.

Keywords: Gabapentin, matrix tablet, sodium alginate, Cellulose acetate phthalate.

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