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A REVIEW ON ANALYTICAL TECHNIQUE FOR ESTIMATION OF ANTI RITROVIRAL DRUG-RITONAVIR
Nidhi Patel Shaileshbhai* and Dr. Neha Tiwari
ABSTRACT Until now after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti-HIV compounds have been formally approved for clinical use in the treatment of AIDS. These compounds fall into six categories: Nucleoside reverse transcriptase inhibitors (NRTIs):- zidovudine, didanosin, zalcitabine, lamivudine, abacavir, stavudine, and emtricitabine nucleotide reverse transcriptase inhibitors (NtRTIs):- tenofovir nonnucleoside reverse transcriptase inhibitors (NNRTIs):-efavirenz, nevirapine, delavirdine, and etravirine. Protease inhibitors (PIs):- ritonavir, indinavir, saquinavir, nelfinavir, amprenavir, lopinavir, fosamprenavir, atazanavir, tipranavir and darunavir. Fusion inhibitors (FIs):- enfuvirtide. coreceptor inhibitors (CRIs):- maraviroc. integrase inhibitors (INIs):- raltegravir). Keywords: HIV, mechanism of action, work on HPLC, literature, drug profile. [Download Article] [Download Certifiate] |