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METHOD DEVELOPMENT AND VALIDATION FOR MELOXICAM AND IBUPROFEN IN COMBINE PHARMACEUTICAL DOSAGE FORMS BY RP – HPLC
*Shaik Murtuza and S. Harshini M.Pharm
ABSTRACT A new method was established for simultaneous estimation of a Meloxicam and Ibuprofen by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Meloxicam and Ibuprofen by using: - Inertsil -ODS C18(250 x 4.6 mm, 5μ), - flow is 1.0 ml/min. - mobile phase ratio was Water and Acetonitrile (80:20). - detection wave length was 220 nm. Keywords: ? Meloxicam and Ibuprofen, ? RP-HPLC, ? Acetonitrile. [Download Article] [Download Certifiate] |