Abstract

A VALIDATED RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF OMEPRAZOLE AND CINITAPRIDE IN BULK AND COMBINED PHARMACEUITCAL DOSAGE FORMS

Santhosh Illendula*, Dasoju Shiva Shankar Prasad and Dr. Rajeswar Dutt

ABSTRACT

Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.[1]

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