Abstract

STUDIES ON CHARACTERIZATION AND IMMUNOMODULATORY SCREENING OF TECOMA STANS AND PHYSALIS MINIMA

K. Sunitha* and M. Nagulu

ABSTRACT

In biology, immunity is the balanced state of having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases. All drugs which modify immune response generally categorized as immunomodulators. These can either function as immunostimulants or immunosuppressants. Immunology is one of the most rapidly developing areas of medical biotechnology research. All drugs which modify immune response generally categorized as immunomodulators. In the present study, Phytochemical screening included extraction, isolation and identification bioactive compounds of methanolic extract of leaves of Tecoma stans and unripe fruits of Physalis minima by different analytical methods. The isolated compounds were screened for immunomodulatory activity. It has been concluded that the isolated components from methanolic extract of leaves of Tecoma stans and unripe fruits of Physalis minima possess alkaloids which may be used to treat different ailments and showed significant immunostimulant properties.

Keywords: Phytochemical, Tecoma stans, Physalis minima, Immunomodulatory activity.