Abstract

EVALUATION OF WOUND HEALING PROPERTY OF PHARMACEUTICALLY PREPARED ETHANOLIC EXTRACT OF OSBECKIA CHINENSIS

Karsang Ghising*, Pujan Karki, Renu Yonjan, Padma Prajapati, Pradeep Giri

ABSTRACT

Objective: Objective of the project is to identify the chemical constituents of Osbeckia chinensis and evaluate their efficacy on wound healing by formulating their extract. Methods: In the experiment, plants were collected, dried, formulated chemically and applied to the wound of mice. Thirty mice were taken for the experiment. Each mouse was divided into five groups. The result was expressed in mean (±) standard error of the mean (S.E.M) for six animals in each group. The data were statically evaluated by one way analysis of variance (ANOVA) followed by Tukey's pairwise comparison test. Results: The result in the project shows that there is asignificant effect of the plant on wound healing. As compared to the standard drug (mupirocin), the plant extract shows a relatively similar effect. Conclusions: Plant extract shows a significant effect on wound healing as compared to the marketed drug (mupirocin). As from the result, it is concluded that Osbeckia chinensis has an anti-microbial property and plays a significant role in wound healing.

Keywords: Osbeckia chinensis, phytochemical screening, wound healing.