Abstract

A BRIEFE REVIEW ON LULICONAZOLE: AN ANTIFUNGAL AGENT

Puja S. Patel*, Dr. S. P. Pawar and V. H. Jain

ABSTRACT

Luliconazole is an agent has been found to have broad spectrum of antifungal activity against pathogenic fungi especially dermatophytes. It is indicated for the treatment of athlete’s foot, jock itch and ringworms caused by dermatophytes such as Trichophyton robrum, Microsporum gypseum anf Epidemophyton floccosum. It firstly approved by FDA in 14 november 2013. It is sold under the brand name LUZU. Luzu has been extensively studied in the US, with three positive pivotal studies that were the basis for approval. Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. This Compound is belongs to the class of organic compounds known as dichlorobenzene. These compounds contain a benzene with exactly two chlorine atom attached to it.

Keywords: Luliconazole, Tinea pedis, Dermatophytosis etc.