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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF TADALAFIL IN BULK AND TABLET DOSAGE FORM

Shrishail M. Ghurghure, Priyanka R. Surwase*, Mahewash A. Pathan, Prasad M. Gote, Dr. Kirtee M. Gaikwad

ABSTRACT

UV spectroscopic method have been developed and validated for the determination of Tadalafil in bulk and tablet formulation. The λmax was found to be 284nm in methanol. Beer’s law was obeyed in the concentration range of 2-10μg/ml. Good accuracy (105%), precision (%RSD0.368), LOD (0.2012), LOQ (0.364) and linearity (0.999) were obtained. The result of analysis has been validated as per the ICH guidelines. The developed method is simple, selective and reproducible and can be used for routine of analysis of formulations containing Tadalafil.

Keywords: Tadalafil, spectrophotometric validation, tablet dosage form.

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