Abstract

CASIA TORA: A PHYTOCHEMICAL SCREENING AND IN VITRO ANTHELMINTIC ACTIVITY OF IT’S AERIAL PARTS (LEAVES)

Abinash Kumar Sahu*, Pratyush Kumar Tripathy, Prabhat Kumar Sahu and Priyanka Joshi

ABSTRACT

Most of the traditional medicines are the most powerful source of biological activity. Ethnopharmacology is not just a science of the past using an out molded approach. It still constitutes a scientific backbone in the development of active therapeutics based upon traditional medicine. Natural products & especially those derived from higher plants have historically played a pivotal role in the discovery of new pharmaceuticals. Aim: The aim of the study is to investigate phytochemical screening of Petroleum ether and aqueous extract of Cassia tora and the presence of different secondary metabolites responsible for the therapeutic values of the drug like presence of Alkaloids, Glycosides, Carbohydrate, Tannins, Phenolic compounds, Proteins & Amino acids, Gums & mucilage, flavours & flavonoids, saponins and steroids & sterols etc and also to find out the anthelmintic activity study by in-vitro test species Pheretima posthuma responded towards our plant extracts by showing the sign of paralysis and death finally Result: The Petroleum ether and aqueous extract yield was 10.93% w/w and 5.43% w/w. It showed the presence of alkaloids, glycosides, saponins, anthraquinone, terpenoids, phlobatanin like compounds but do not shows the presence of carbohydrate in Petroleum ether, phenolic, flavonoid and lignin. Conclusion: It showed the presence of alkaloids, glycosides, amino acids, saponins, Carbohydrate, anthraquinone, protein and amino acids like compounds. And the data revealed that the aqueous extract of Cassia tora (leaves) showed more potent anthelmintic activity as compared to petroleum ether extract.

Keywords: Cassia tora, Phytochemical, Albendazole, Anthelmintic Activity, Pheretima posthuma.