HEALING POTENTIAL OF RHEUM EMODI (RHUBARB) ROOT POWDER ON EXCISION WOUNDS IN RABBIT
S. Bilal*, S. A. Bhat, A. A. Ahanger, I. Hussain, S. P. Ahmad4, M. R. Mir
ABSTRACT
Purpose: To evaluate wound healing potential of Rheum emodi roots.
Material Method: Rheum emodi root in powder form was applied on
the excision wounds created in rabbits for 14 days with normal saline
as control. The physico-chemical parameters studied were wound
contraction, and concentration of hydroxyproline, glucosamine, protein
and DNA. Results: On day 14 Rheum emodi treated wounds showed
100 % reduction in the wound area as compared to control 82%. The
treated wounds exhibited significant increase in hydroxyproline
(21.00±0.92 mg/g, treated vs 12.96±0.86 mg/g, control; p
Keywords: Rheum emodi, Wound contraction, Hydroxyproline, Glucosamine, Protein, DNA.
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