Abstract

SUBLINGUAL TABLETS: A REVIEW ON

Vaibhav K. Patil*, Ganesh N. Patil, Sulbha G. Patil, Nilesh P. Salunkhe and Sunil P. Pawar

ABSTRACT

Oral administration is one of the most convenient forms for the intake of drug due to ease of administration, painless, versatility, and paramount patient compliance. The demand of fast disintegrating tablets has been growing, during the last decades especially for geriatric and pediatric patients due to dysphasia. The demand of fast disintegrating tablets has been growing during the last decade, due to the characteristics of fast disintegrating sublingual tablets for the potential emergency treatment. In terms of permeability, the sublingual area of the oral cavity (i.e, the floor of the mouth) is more permeable than the buccal (cheek) area, which in turn is more permeable than the palatal (roof) of the mouth. Drug delivery through the oral mucous membrane is considered to be a promising alternative to the oral route. These tablets disintegrate and dissolve rapidly in saliva due to interaction with our salivary enzymes.

Keywords: Sublingual drug delivery, Improved bioavailability, Tecnique, Evaluation.