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METHOD DEVELOPMENT OF METFORMIN HYDROCHLORIDE RP-HPLC
Gadipally Saikiran*
ABSTRACT A simple, specific, accurate and precise Reverse Phase High Performance Liquid Chromatographic method was developed metformin hydrochloride in tablet dosage form on RP Kromasil -ODS C18 using mobile phase as Methanol:orthophosphoric acid (50:50)The flow rate was 1.0 ml/min and effluent was monitored at 270nm. The retention time is 2.3 respectively. Keywords: metformin hydrochloride Reverse Phase High Performance Liquid Chromatography. [Download Article] [Download Certifiate] |