Abstract

DEVELOPMENT OF FLOATING TABLETS DOSAGE FORM OF THEOPHYLLINE

Neelmani Chauhan*, J. E. Rachel Nivedita, S. Sravanthi and H. Padmalatha

ABSTRACT

The objective of this research work was to formulation and evaluation the floating drug delivery system containing theophylline as an optimize the drug release profile. Theophylline tablets were prepared by direct compression. Formulation contains Acacia Gum, Tragacanth Gum, Xanthan Gum, and gas generating agent such as sodium bicarbonate was taken independent variables. The effect of formulation variable on floating and drug release was evaluated. The pre compression and post compression parameters were evaluated within limits. The F8 formulation was showed good release 99.58% and it consider as an optimized.

Keywords: Theophylline, floating tablets, Tragacanth gum, Dissolution rate.