Abstract

SCIENTIFIC VALIDATION OF A NOVEL PLANT (CROTOLARIA GENISTOIDES) TO EXPLORE THE WEALTHINESS OF SIDDHA PHARMACOLOGY FOR ITS HYPOGLYCEMIC EFFECT- AN IN VITRO ASSAY

S. Mohamed Ajmal*, M.R. Saravanan, M. Revathi

ABSTRACT

Introduction: Siddha is the first and foremost traditions of healthcare with many therapeutic benefits. There is lot of scope and opportunities for Siddha. Only there is lack of scientific validations at various levels. In the plant kingdom there is remedy for every diseases. WHO estimates that 80 percent of the people in the developing countries of the world rely on traditional medicines for healthcare. Methodology: Plant extracts were made from the different solvents to get the detailed information about the phytochemicals present in the plant. Activity guided fractionation is the method employed to identify biologically active compound using Column chromatography, GCMS and then glucose diffusion and alpha amylase experimentation is for a pharmacological action of the fractioned compound. Result and Discussion: From this technique, it is revealed that chemical compound are separated and the glucose inhibitory test shows Crotolaria genistoides to have maximum inhibitory effect to the diffusion of glucose across dialysis membrane but it showed the least inhibition of alpha amylase activity. Conclusion: Thus, this exploration of this chemical compounds possess hypoglycemic effect and pave the way to increase the scope of Siddha medicine.

Keywords: Siddha, WHO, Crotolaria Genistoides, Hypoglycemic Effect.