Abstract

A COMPARATIVE STUDY OF CEFOTAXIME AND CEFTRIAXONE IN SURGICAL PROPHYLAXIS FOR CLEAN HERNIA SURGERY

Dr. G. Ravishankar*, S. Rajarajan M. Pharm, Lekshmi R. Nair, Sinu M. Saju, Dr. V. Ganesan and M. Pharm PhD

ABSTRACT

Background: The defect in the collagen metabolism is involved in the pathogenesis of hernia which lead to a weakening of the transversalis fascia. Hernia is the most common surgery performed by general surgeons and which have many advantages, such as effectiveness, simplicity, minimal pain, and low recurrence rates, early return to work and a high patient satisfaction. In which Lichtenstein technique is frequently used method. Objective: To conduct a comparative study of cefotaxime and ceftriaxone in surgical prophylaxis for clean hernia surgery. Patient and Methods: An experimental prospective study conducted over a period of 8 months from 2017-2018. In which 100 patients were divided into two groups. The cases were compared on the basis of age, ASA grading, gender, comorbidities, radiological assessment which directly or indirectly affect the occurrence of surgical site infections were also considered. Furthermore; Chi-square test has been used to find out the statistical significant relation. Result: We found that, 100 patients were divided into two groups. The patients 50-59years(26%) were more prone to hernia than those ranging from

Keywords: Cefotaxime, Ceftriaxone, Hernia, Lichtenstein technique.