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Abstract

METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF DIPHENHYDRAMINE AND NAPROXEN BY USING RP-HPLC METHOD IN BULK AND PHARMACEUTICAL DOSAGE FORMS

P. Sathya Narayana*, J. China Babu, D. Balaji, A. Ramadevi and R. Ananta Kumar

ABSTRACT

The main aim of present analytical research is to develop a simple, accurate, rapid and economical RP-HPLC method for the simultaneous estimation of Diphenhydramine and Naproxen in bulk and pharmaceutical dosage forms . The drug analysis plays an important role in the development, manufacture and therapeutic use of drug. To validate the method according to ICH guidelines.

Keywords: Diphenhydramine, Naproxen, Methanol, Buffer.


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