Abstract

A REVIEW ON PROTON PUMP INHIBITORS INDUCED DISEASES

Y. Narasimaha Rao*, Sirisha Chinta, K. J. S. V. Sireesha, Vinitha Sakhamuri, Sravanthi Vittala, Lavanya Thota

ABSTRACT

The proton pump inhibitors are most effective and mostly prescribed drugs in the clinics now-a-days and also used during multi drug therapy. They have a greater degree and longer duration action when compared to H2-receptor antagonist. Most commonly used drugs in PPI’s are pantoprazole and rabeprazole. Due to the increased prescription of these drugs for longer durations can alter the health related life of the individuals. Long term use of these drugs may cause some disorders like PPI induced effect on mineral absorption& iron absorption, PPI induced enteric infections, PPI induced osteoarthritis, Dementia. So there is a major scope in knowing the long term effects of Ppi’s.

Keywords: Health related life, long term effects, and Proton pump inhibitors.