Abstract

A RETROSPECTIVE OBSERVATIONAL STUDY OF CLINICAL PROFILE AND COMPLICATIONS OF DENGUE FEVER

Dr. S. E. Bharanidharan*, Dr. R. Senthilselvi M. Pharm, PhD., Merlin Antony Pharm. D, Silpa Jose Pharm. D, Dr. V. Ganesan., M. Pharm

ABSTRACT

Background: Dengue fever is one of the major public health problems in Tamil Nadu. The present study was conducted with an objective to study the clinical profile and complications of dengue fever. At times platelet count which is one of the major accessory laboratory test to detect the dengue fever. All cases were presented with fever similar studies in and around India have also highlighted fever as a common presenting symptom. In our study other major presenting symptoms were vomiting/abdominal pain, headache, purpura/petechiae, melena, hepatomegaly, bodypain, hypotension, myalgia, hematuria. Hepatic dysfunction and acute renal failure were the major complications observed in our study. A total of 94 cases were subjected to IgM antibodies and NS1 antigen testing method. There is no association between age and complications(p value0.142>0.05).Complications reported in our study has no association with platelet range (p value0.593>0.05) because the complications observed in present study is very less and we concluded that there is an association between bleeding and dengue hemorrhagic fever. In this paper clinical manifestations and management of dengue/dengue hemorrhagic fever/dengue shock syndrome.

Keywords: Dengue fever, dengue hemorrhagic fever, dengue complications, clinical manifestations.