Abstract

TOXICOKINETIC EVALUATION IN PRECLINICAL STUDIES

Nidhi Mishra* and Agrima Srivastava

ABSTRACT

Toxicokinetic assessment is both a monitoring or scientific necessity in the drug advancement method. Toxicokinetic is the age of dynamic data to evaluate systemic introduction, either as an essential part of preclinical toxicity studies, or in specifically planned supportive studies. These information help to comprehend the connection between detected toxicity or administered dose. They additionally assume a role in the clinical setting, supporting in the setting of plasma limits for early human introduction and in the estimation of protection limits.

Keywords: .