Abstract

A REVIEW: FIXED DOSE COMBINATIONS OF PENICILLINS

Mohini S. Jogdande* and Sachin A. Nitave

ABSTRACT

A combination drug is a fixed dose combination (FDC) that includes two or more active pharmaceuticals ingredients (APIs) combined in a single dosage form, which is manufactured and distributed in fixed doses. Antibiotics also called antibacterials are a type of antimicrobial drug used in the treatment and prevention of bacterial infections. They may either kill or inhibit the growth of bacteria. In the management of adverse drug reaction and to control the side effects of the drug fixed dose combination formulations have their usefulness. Fixed dose combinations can also deal with pill burden in long term treatment. fixed dose combinations of penicillins can apply to fulfill the patient compliance, provide high therapeutic index and to provide cheaper medicines to the patient.

Keywords: FDC, antibacterial, antibiotics, penicillins, patient compliance, therapeutic index.