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  • WJPPS JANUARY ISSUE PUBLISHED
  • JANUARY 2019 Issue has been successfully launched on 1 January 2019

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

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  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
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  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
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Abstract

NOVEL SYNTHESIS OF 8, 9-DIHYDRO- 7H-BENZO 4-METHYL-2-OXO-2H-8-CHROMENYL] 5-ARYL-4, 5-DIHYDRO-4-ISOXAZOLE CARBOXYLATES

Dr. A.L.V. Ramana Reddy*

ABSTRACT

8, 9-dihydro- 7h-benzo -4-methyl-coumarin aldehyde chlorooxime (4) on reaction with in the presence of polyphosperic acid reflus for 24 hours to gave 8, 9-dihydro- 7h-benzo chloro-4-methyl-2-oxo-2H-8-chromenyl]-5-phenyl-4,5-dihydro-4-isoxazole carboxylate (5a-h) in a good yields. The structures of all the newly synthesized molecules were assigned by elemental analysis and spectral data. The synthesized compounds were screened for their antibacterial activities strains using Cup plate method.

Keywords: 7-Benzyloxy-4-methyl-coumarin aldehyde chlorooxime, triethylamine in chloroform, aldehyde chlorooxime, antibacterial activity.


[Full Text Article]

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