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  • WJPPS NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2018 Issue has been successfully launched on 1 November 2018

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  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

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Abstract

IN SILICO STUDIES ON DENGUE AND MERS CORONAVIRUS PROTEINS WITH SELECTED CORIANDRUM SATIVUM L. HERB CONSTITUENTS

Sheetal. V. Rao, Tulasi D. P., Pavithra K., Nisha R., Rameen Taj S., *Balasubramanian Sathyamurthy

ABSTRACT

Dengue virus contains seven proteins and MERS coronavirus contains six proteins which are considered to be the most effective for drug designing. Phytochemicals present in Coriandrum sativum L. function as aromatizing agents and has relaxant activity in the alimentary tract. They are found to have great antibacterial and anticancerous properties. In this study, the binding efficiency of 4 compounds present in the Coriandrum sativum L. with all the thirteen proteins of dengue as well as MERS corona virus were performed through In silico methods. By our virtual screening and molecular docking result, we found that Dodecanal has the highest binding affinity with all the viral proteins.

Keywords: Coriander, molecular docking, Phytochemicals, Dodecanol.


[Full Text Article]

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