Photo Gallery

Login

Search

News & Updation

  • WJPPS NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2018 Issue has been successfully launched on 1 November 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

VALIDATED SPECTROPHOTOMETRIC QUANTITATION OF LEVOFLOXACIN IN BULK AND TABLET DOSAGE FORM

Pooja M.*, Sowmya H. G. and Jose Gnana Babu C.

ABSTRACT

A novel, simple, accurate and precise Zero order derivative spectroscopic method was developed and validated for the estimation of Levofloxacin in bulk and Pharmaceutical dosage forms and has an absorption maximum at 293.6 nm in 0.1N Sulphuric acid. The Linearity was found to be in the concentration range of 5-30μg/ml and the correlation coefficient was found to be 0.999 and it has showed good linearity, reproducibility, precision in this concentration range. The regression equation was found to be Y = 0.019 X + 0.003. The % recovery values were found to be within 99.14 -100.16 % showed that the method was accurate. The LOD and LOQ were found to be 0.3041 and 0.9123μg/ml, respectively. The % RSD values were less than 2. The method has been validated according to ICH guidelines for linearity, accuracy, precision, robustness, ruggedness. Limit of detection and limit of quantitation. Proposed method was successfully applied for the quantitative estimation of Levofloxacin in bulk and pharmaceutical dosage form.

Keywords: Levofloxacin, Zero order derivative Spectroscopy, 0.1N Sulphuric acid, Linearity, Precision, Reproducibility, and Accuracy.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More