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  • WJPPS NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2018 Issue has been successfully launched on 1 November 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

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  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
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  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
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Abstract

TECHNIQUE TO ENHANCE THE BIOAVAILABILITY AND SOLUBILITY FOR POORLY WATER SOLUBLE DRUGS BY USING: SOLID DISPERSION

Mohd. Asad Farooqui*, Dilip Km. Patel and Roohi Kesharwani

ABSTRACT

Solid dispersions of poorly water-soluble drugs with water-soluble carriers have been reduced the incidence of these problems and enhanced dissolution. The focus of this review article on advantages, disadvantages and the method of preparation, and characterization of the solid dispersion. The solubility issues complicating the delivery of these new drugs also affect the delivery of many existing drugs. The various techniques are available for enhancement of solubility. Solid dispersion is one of the most promising approaches for solubility enhancement. Currently only 8% of new drug candidates have both high solubility and permeability. More than 60% of potential drug products suffer from poor water solubility.

Keywords: Solubility, Solid Dispersions, Carrier, Bioavailability Hydrophilic, Fusion method.


[Full Text Article]

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