Abstract

COMPARATIVE PHYTOCHEMICAL SCREENING AND IN VITRO ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF AEGLE MARMELOS (L) CORR

Sneha Joshi*, Rajni Dhiman and Anjali Singh

ABSTRACT

Context: The use of traditional medicine has increased in developed countries also, mainly due to failure of modern medicine to provide effective treatment for chronic diseases and emergence of multi-drug resistant bacteria and parasites. Aim: The present study was designed to detect preliminary phytochemicals and antimicrobial activity of Aegle marmelos (L) corr. against pathogenic strains of gram negative Escherichia coli (1687), and gram positive Enterococcus fecalis (439). Material and methods: The antimicrobial activity of the organic solvent extracts of Aegle marmelos was investigated using Cylinder -plate or Cup-plate method. Results: Preliminary phytochemical screening suggests that there is similarity in phytochemical profile of leaf, stem and unripe fruit. Phytochemical analysis shows that Starch, Tannin, Flavonoid and Favanol are present in higher amount in the leaves whereas Sugar and total Phenolics contents are present in higher amount in unripe fruit of Aegle marmelos. The present study indicated the presence of phytoconstituent like tannins, Glycoside, flavanoids, alkaloids, proteins, free amino acids, phenols and carbohydrates in Aegle marmelos (leaf, stem and unripe fruit). Conclusion: Above study illustrates that all that the leaves, stem and fruit of Aegle marmelos possess considerable antioxidant and antibacterial activity. Although, the leaves was found to be possess significantly higher antibacterial as well as antioxidant activity as compared with the fruit or stem. Preliminary photochemical screening suggests that there is similarity in photochemical profile of leaf and unripe fruit.

Keywords: Aegle marmelos (L) corr., Antimicrobial, Pathogenic.