Photo Gallery

Login

Search

News & Updation

  • WJPPS NOVEMBER ISSUE PUBLISHED
  • NOVEMBER 2018 Issue has been successfully launched on 1 November 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

INCIDENCE AND RISK FACTORS FOCUSING ON RADIOLOGY: REACTIONS AFTER EXPOSURE TO NON-IONIC CONTRAST MEDIA

Milena Theodoro, Daniele Cardoso dos Santos, Gabriel Teixeira Cagnin, Fabíola Garcia Praça and Wanessa Silva Garcia Medina*

ABSTRACT

Computed tomography (CT) imaging has rapidly become a commonplace diagnostic tool due to its utility in a wide range of diseases. To prospectively evaluate the incidence of reactions after exposure to Non-Ionic Contrast media (NICM), and to identify potential risk factors, with a focus on fasting duration for solid food and fluids, separately. Methods: From July to October 2017, 229 patients (117 men, 112 women; median age, 53.2 years; range, 04-90 years) undergoing ICM-enhanced CT were included in this study. Reactions after exposure to ICM exposure were assessed on a 3-point scale (mild, moderate, severe). Patients’ characteristics and the fasting duration were evaluated to identify risk factors using logistic regression analysis. Results: Of the 229 patients, 8 experienced hypersensibility reaction, no patients experienced vomiting. Multi-variate regression analysis revealed that a history of drug hypersensitivity (3.49%) was independent risk factors for nausea. Of the patients who presented hypersensitivity reactions, 12.5% were diabetic, 12.5% had asthma, 50% had systemic arterial hypertension, 50% had dyslipidemia, 0% had renal disease, 25% had no associated alterations (asthma, hypertension, diabetes, dyslipidemia, renal diseases. Conclusions: The adverse reactions to ICM agents were consisting in predictors analyzers like an allergic history to contrast agents, diabetic, asthma, systemic arterial hypertension, dyslipidemia, renal disease and urticaria, history of the previous allergy to drugs other than contrast agents. ICM Hypersensitive reactions occurred in 1.31% of patients. Our results showed that clinical decision based on patient clinical records resulted in a decrease of several immediate reactions incidence.

Keywords: Hypersensitivity reaction, iodinated contrast media, non-ionic contrast media, case report, clinical history.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More