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Abstract

SYSTEMATIC EVALUATION OF EXCLUSIVE FACTORS ASSOCIATED WITH NON-ADHERENCE TO TREATMENT IN IBD PATIENTS

Bandari Madhuri*, Mudigonda Shirisha Yadav, Potharla Ajay Kumar, Vishlavath Ganesh Naik, Dr. Rupa Banerjee and Dr. A. Srinivasa Rao

ABSTRACT

Adherence to treatment is a key condition in preventing relapses in inflammatory bowel disease. This study was contrived with the aim to evaluate the exclusive factors associated with non-adherence to treatment in Inflammatory Bowel Disease. A total population of 150 patients were evaluated for this study from Asian Institute of Gastroenterology, to find out the factors causing non-adherence to treatment. A questionnaire concerning demographic, clinical, patient related, medication related, physician related, socioeconomic and psychological assessment of patients were evaluated by using Microsoft Excel 2007. Out of 150 patients 89(59.3%) men and 61(40.6%) women completed the questionnaire. Patients with Crohn’s disease 73(48.6%), indeterminate colitis 4(2%), and ulcerative colitis 73(48.6%). In patient related factors, non-adherence causing co-factors were diminished quality of life 91(60.67%) (60.67%) , full time employment 81(54%) (54%)(54%), and lack of understanding the drug use 80(53.3%) (53.3%)(53.3%). In medication related factors, high cost 102(68%), (68%), non-availability of medication 78(52%) (52%), heavy pill burden 76(50.6 %) . In physician related factors, lack of explanation about side-effects 91(80.67%) (80.67%) . In psychological assessment, health dependent on medication 97(64.66%), (64.66%), (64.66%), prefer once daily medication 96(64%) (64%), effect of medicine on future health 89(59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%)(59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%) (59.33%), mystery to take medication 46(30.66%). In socioeconomic factors, lack of participation in sports/activity 44(29.33%) (29.33%) (29.33%), going out socially 45(30%) (30%), worried about future income 63(42%) (42%) causing non adherence in patients. Conclusion: In this prospective observational study, socioeconomic factors were causing the non-adherence to treatment due to high cost of the medication which can be overcome by prescribing generic drugs, low cost medication. Patient counseling and patient education will enhance the quality of life of patients.

Keywords: Adherence, Non-adherence, Ulcerative Colitis, Crohn’s disease, Medication, Treatment.


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