Photo Gallery

Login

Search

News & Updation

  • WJPPS SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2018 Issue has been successfully launched on 1 September 2018

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

COMPARATIVE ANTIULCER ACTIVITY OF PULP & SEED OF ETHANOLIC EXTRACTS OF CUCUMIS MELON (LINN) IN RATS

Veer Bala* and Nidhi Tyagi

ABSTRACT

The present study was undertaken to investigate antiulcer effect of ethanolic extracts of pulp & seed of Cucumis melon L. in Wistar rats. Ethanolic Pulp extract of Cucumis melon L. was administered to experimental rats at doses of 200 and 400 mg/kg. & ethanolic seed extract was administered at doses of 200 and 400 mg/kg. Standard drug was Ranitidine (50mg/kg) while normal saline (0.9%) was used as control. The antiulcer effect of the extracts was evaluated measuring different parameters like free acidity, total acidity, ulcer index, ulcer score, gastric secretion and pH of the gastric juice. In addition, total acidity and free acidity were also reduced significantly (**P<0.01, *P<0.05) in dose dependent manner. Further it was observed that ulcer index and ulcer score of extract treated and standard were also reduced significantly (P<0.01) as compared to control group (9.83±1.20, 3.28±0.39). We can conclude that ethanolic extracts of pulp & seed of Cucumis melon L. produced notable antiulcer effect which appeared to be comparable with the effect produced by the standard (Ranitidine). The present study provides a quantitative basis for explaining the folkloric use of Cucumis melon L. as an Antiulcer agent.

Keywords: Herbal medicine, Cucumis melon L., Ethanolic extract, Antiulcer activity.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More